Pueraria tuberosa is a medicinal plant used in the Indian traditional system of medicine. It is a source of Puerarin which is an isoflavone. Puerarin has been reported to possess anti-fertility, anti-hypertensive, anti hyperglycemic, nootropic and neuroprotective effects. Previous studies indicated the potential actions of P. tuberosa as an antioxidant that normalizes the hypoxic stress induced elevation of lipid peroxides and catalase and cold immobilization stress (3). The powder of Pueraria tuberosa root-tubers is in clinical use as antiaging and also as tonic, aphrodisiac, demulcent, lactagogue, purgative, cholagogue and also in scorpion sting. Besides, it is also useful in emaciation of children, debility and poor digestion. Other investigators have reported it for skin care, as anti-fertility. One of its phytochemical, purerin, has been associated with antidiabetic property. Puerarin and its preparations (injections) are official in Chinese Pharmacopeia. Its pharmacological activities like: anticancer, hepatoprotective, estrogenic, antioxidant, antidiabetic, neuroprotective and in learning-memory disorder have been reported. In a recent study a plant Pueraria tuberosa popularly used in folklore medicine is reported for its nerve tonic, anti-inflammation brain tonic, galactogauge and as a mind power syrup in ayurvedic formulation. (2, 4)
P. tuberosa extract significantly lowered the serum cholesterol, triglycerides, LDL- and VLDL-cholesterol in rats maintained on high cholesterol diet. There was no significant increase in HDL cholesterol levels on administration of the extract. The lipid lowering effect of P. tuberose may be attributed to isoflavones present in the tubers. This study scientifically validates the use of Indian kudzu with high caloric (high fat) diet having beneficial effects on lowering the lipid profile.