Open Login Screen

Vidharikand

56.png
Pueraria tuberosa is commonly known as kudzu or Indian kudzu. It is a climber with woody tuberculated stem. It is a climbing, coiling and trailing vine with large tuberous roots belongs to the genus Pueraria and family Fabaceae. The tubers are globose or pot-like, about 25 centimetres across and the insides are white, starchy and mildly sweet. Leaves are trifoliate and alternate, while the leaflets are egg-shaped, with round base and unequal sides. It is native to India, Pakistan, and Nepal.
Favoured:
0

Listing Details

Botanical Names
Pueraria tuberosa
Indian Names
Sanskrit : Vidari Assam : Bhedeleton Bengali : Vidari Gujarati : Vidarikand Hindi : Vidarikand Kannada : Nelagumbalagudde Malayalam : Mudakku Marathi : Bhuikohala Tamil : Nilapoosani Telugu : Nelagummuda
Chemical Constituents
The chemical constituents of Pueraria tuberoa have been identified as puerarin, diadzein, daidzin, â-sitosterol and sigmasterols. It’s major chemical constituents include flavones C-glycoside, Isoflavones (Puerarone), Coumstan (Tuberostan, Puerarostan), Epoxychalcanol [Puetuberosanol], (3’- hydroxy-4’-phenoxy-a,b-epoxychalcan-a’ol)], Pterocarpanoids [Hydroxytuberosin, Anhydroxytuberosin (3-O-methylanhydrotuberosin)], and Tuberosin (1). It also contains Phytoconstituents like β- sitostreol, stigmasterol, puerarone and coumestan, isoflavone C-glycoside-4,6-diacetyl-puerarin, pterocarpintuberosin, puetuberosanol and hydroxytuberosone have been isolated and characterized from the species.
Pesticide Limits
A limit for pesticide is one of the major issues in standardization of medicinal plants and products in view of the worldwide widespread use of pesticides in cultivated plants. The presence of pesticides in extracts increase the health risk by many folds. The pesticides can be extremely irritant on skin as well as in the internal organs hence it is essential to monitor its concentration as a part of GMP. Various analytical methods for the quantitative determination of pesticides by gas chromatography coupled with mass-spectrophotometer are in use. Konark Research Foundation (KRF), a NABL certified lab is well equipped with the latest technology and instruments and monitors the pesticide limit as part of its GMP.
Chromatographic Profile
From the pharmacopoeial perspective, a better quality control of raw material can be achieved by specifying quantitative test procedure for the determination of the range or a minimum content of the active ingredient or marker substances. A chromatographic finger profile represents qualitative/ quantitative determination of various components present in a complex plant extract, irrespective whether or not their exact identity is known. Thin layer chromatographic technique is the simplest and least expensive method that provides plenty of information on the composition of raw herbs and its preparation. For quantitative analysis of active ingredients or marker substances with simultaneous separation and detection High Pressure liquid chromatography is the best technique. We use the latest model of HPLC for all its analysis.
Limits of Impurities
A test requirement for foreign organic matter would ensure the extent of contamination of extraneous matters such as filth and other parts of botanicals not covered by the definition of the herbal drug. Since sand and soil are predictable contaminants of botanicals, test requirements for ‘total ash’, water soluble ash’, ‘acid soluble ash’, residue on ignition and sulphated ash would be expected to limit such contaminants. Test requirement for heavy metals in botanical raw material are probably more relevant for parts of plants growing under ground than for the aerial parts of the plant. The presence of high levels of minerals interacts with the final product there by affecting its keeping quality.
Microbial Limits
If the raw herbs are to be used directly without boiling in water prior to consumption, restrictive limits on microbial contaminants are required for pathogens such as Salmonella sp. Enterobacter and E. coli which are causative agent for various gastrointestinal diseases. A lower level of yeasts and molds and a limit on total aerobes are considered appropriate in plant material for topical use. The presence of aflatoxins detected by chemical means is generally independent of the number of viable molds that are detected using microbiological methods. Aflatoxins in microgram quantity are capable of giving serious hypersensitivity reactions which can be extremely harmful to human health.
Pharmacology
Pueraria tuberosa is a medicinal plant used in the Indian traditional system of medicine. It is a source of Puerarin which is an isoflavone. Puerarin has been reported to possess anti-fertility, anti-hypertensive, anti hyperglycemic, nootropic and neuroprotective effects. Previous studies indicated the potential actions of P. tuberosa as an antioxidant that normalizes the hypoxic stress induced elevation of lipid peroxides and catalase and cold immobilization stress (3). The powder of Pueraria tuberosa root-tubers is in clinical use as antiaging and also as tonic, aphrodisiac, demulcent, lactagogue, purgative, cholagogue and also in scorpion sting. Besides, it is also useful in emaciation of children, debility and poor digestion. Other investigators have reported it for skin care, as anti-fertility. One of its phytochemical, purerin, has been associated with antidiabetic property. Puerarin and its preparations (injections) are official in Chinese Pharmacopeia. Its pharmacological activities like: anticancer, hepatoprotective, estrogenic, antioxidant, antidiabetic, neuroprotective and in learning-memory disorder have been reported. In a recent study a plant Pueraria tuberosa popularly used in folklore medicine is reported for its nerve tonic, anti-inflammation brain tonic, galactogauge and as a mind power syrup in ayurvedic formulation. (2, 4) P. tuberosa extract significantly lowered the serum cholesterol, triglycerides, LDL- and VLDL-cholesterol in rats maintained on high cholesterol diet. There was no significant increase in HDL cholesterol levels on administration of the extract. The lipid lowering effect of P. tuberose may be attributed to isoflavones present in the tubers. This study scientifically validates the use of Indian kudzu with high caloric (high fat) diet having beneficial effects on lowering the lipid profile.
Health Benefits
ueraria tuberosa is a perennial climber found throughout the Indian subcontinent in wet and damp areas. Pueraria tuberosa is the important plant used in Indian medicine, commonly known as Vidarikand. The tuberous roots of this plant are used in Indian traditional medicine (Ayurveda) in general debility, nervous breakdown, spermatorrhoea, burning sensation, heart diseases, intrinsic hemorrhage, and tuberculosis. The plant is described as rasayana and tonic in Ayurvedic Pharmacopoeia of India. The tuber of pueraria is sweet in taste and used in indigenous system of Indian medicine as tonic, aphrodisiac, antirheumatic, diuretic and galactogogue. It is an important constituent of Ayurvedic medicines including Chywanprash, a popular tonic (2, 3). Puerarone is an isoflavones a major bioactive component of Pueraria tuberose isoflavones are protective antioxidants. The antioxidant and other activities of phenolics are based on their ability to donate hydrogen atom to free radicals. Due to these properties isoflavones are believed to have potential in the prevention of cancer, atherosclerosis and diabetes. Much pharmacological work has been carried out on isoflavones present in soya food and Chinese material (P. lobata) and properties such as antihyperglycemic, antioxidant, hepatoprotective and estrogenic effects have been reported (5). In the Ayurvedic system of medicine, it is used as a drug of choice to manage pain, inflammation and other related diseases. The antioxidant potency of P. tuberosa was investigated for the first time. Hexane and methanol fractions inhibited lipid peroxidation, showing potent antioxidant property.
Research References
1. Nidhi P. and Yamini B. T. Antioxidant activity of tuberosin isolated from Pueraria tuberose Linn Pandey and Tripathi Journal of Inflammation 2010, 7:47 2. NAGENDRA SINGH CHAUHAN*, NISHANT KUMAR GUPTA, VIKAS SHARMA and VINOD KUMAR DIXIT SPECTROFLUORIMETRIC ESTIMATION OF PUERARIN IN PUERARIA TUBEROSA Acta Poloniae Pharmaceutica ñ Drug Research, Vol. 68 No. 3 pp. 453ñ456, 2011 3. SS Pramanik,1 TK Sur,1 PK Debnath2 and D Bhattacharyya1 Effect of Pueraria tuberosa tuber extract on chronic foot shock stress in Wistar rats Nepal Med Coll J 2010; 12(4): 234-238 4. Venkata R., Basavaraj P., Nimbal S. K., Shantakumar S. M. and Satyanarayan S. Nootropic activity of Tuber Extract of Pueraria tuberose Roxb. Indian Journal of Experimental Biology, 2008 46:591-598 5. TANWAR Y.S., GOYAL S. and RAMAWAT K.G. HYPOLIPIDEMIC EFFECTS OF TUBERS OF INDIAN KUDZU (PUERARIA TUBEROSA) Journal of Herbal Medicine and Toxicology 2 (1) 21-25 (2008) 6. Nidhi P., J.K. Chaurasia, O.P. Tiwari and Yamini B. T. Antioxidant properties of different fractions of tubers from Pueraria tuberosa Linn Food Chemistry Volume 105, Issue 1, 2007, Pages 219-222